Health-promoting effects of postbiotic <i>Bacillus subtilis</i> subsp. <i>natto</i>

ZHOU Zhimo; LIU Meixun; JIA Wen; WU Simou; CHEN Jiepeng; LI Ming; SHEN Xi; CHENG Ruyue; HE Fang

doi:10.13381/j.cnki.cjm.202403020

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ZHOU Zhimo, LIU Meixun, JIA Wen, et al. Health-promoting effects of postbiotic Bacillus subtilis subsp. natto[J]. Chinese Journal of Microecology, 2024, 36(3): 368-372. doi: 10.13381/j.cnki.cjm.202403020

Citation:

ZHOU Zhimo, LIU Meixun, JIA Wen, et al. Health-promoting effects of postbiotic Bacillus subtilis subsp. natto[J]. Chinese Journal of Microecology, 2024, 36(3): 368-372. doi: 10.13381/j.cnki.cjm.202403020

Health-promoting effects of postbiotic Bacillus subtilis subsp. natto

1.
Department of West China School of Public Health and West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610041, China

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Corresponding author: HE Fang, E-mail: hf18602880124@163.com

Received Date: 14 February 2024

Revised Date: 01 March 2024

Publish Date: 31 March 2024

Abstract

Abstract

Bacillus subtilis subsp. natto is a probiotic with a long history of consumption, and its safety and health promoting effects have been well proven in both human and clinical trials. Special cultivation and membrane filtration techniques can be used to produce a new type of postbiotic using Bacillus subtilis subsp. natto which contains various unique postbiotic components, such as bacterial wall, extracellular polysaccharides, nattokinase, vitamin K₂, γ-polyglutamic acid and other epigenetic components. These postbiotic components can endow Bacillus subtilis subsp. natto the potential of probiotics with much more unique health promoting functions, such as regulating bowel movements and promoting digestion, preventing and dissolving blood clots, lowering blood pressure, promoting bone calcium absorption, reducing uric acid and inhibiting bacteria and inflammation. This article discusses the definition, preparation methods, functional components and health promoting effects of the postbiotic Bacillus subtilis subsp. natto.
- Probiotics /
- Postbiotics /
- Bacillus subtilis subsp. natto /
- Nattokinase /
- Vitamin K₂ /
- γ-polyglutamic acid

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References

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